Exploring the ethics of genetic prioritisation for COVID-19 vaccinesCOVID-19 백신에 대한 유전적 우선순위의 윤리 탐구Review Published on 2022-03-072022-09-10 Journal: European Journal of Human Genetics [Category] MERS, 바이오마커, 유전자 메커니즘, [키워드] COVID-19 COVID-19 infection COVID-19 vaccine disease Ethics evaluate Evidence Factor Genetic genetic factors genetic marker Genetic markers genomic Health policy Host individual Infection resistance to infection response variability Spread vaccination Vaccine Variability vulnerability [DOI] 10.1038/s41431-022-01058-1 PMC 바로가기 [Article Type] Review
Distinguishing gene flow between malaria parasite populations말라리아 기생충 집단 사이의 유전자 흐름을 구별합니다Research Article Published on 2021-12-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Analysis analyzed approach complementary conditions connectivity death descent disease disease control disperse distinguishing drug-resistant effort epidemiological evaluate gene flow Genetic genetic marker Genetic markers genomic Genomic surveillance geographic location geographic locations Guidance identity implementation implication include Infection information interpretability Interpretation Local malaria malaria control malaria parasite malaria parasites Metrics Migration Multiple National observation observations P. falciparum parasite Population populations public health question sampling sequence similar studies Spread strain Surveillance understanding whole genome sequence [DOI] 10.1371/journal.pgen.1009335 PMC 바로가기 [Article Type] Research Article
Monitoring of SARS-CoV-2 RNA in wastewater as an epidemiological surveillance tool in Mendoza, Argentina아르헨티나 멘도사에서 역학 감시 도구로서의 폐수 내 SARS-CoV-2 RNA 모니터링Article Published on 2021-11-202022-09-11 Journal: The Science of the total environment [Category] SARS, 치료기술, 치료법, [키워드] advance aluminum Analysis applied Concentration COVID-19 COVID-19 case COVID-19 cases diagnosed Epidemiologic surveillance epidemiological epidemiological surveillance Epidemiology exponential growth genetic marker Genetic markers glycol growth Health status increase in individual infections marker MONITOR monitoring N1 and N2 nucleocapsid pandemic plant plateau Polyethylene glycol populations positive correlation quantification RNA isolation RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 RNA spatial information Surveillance Treatment Viral load Wastewater-based epidemiology. [DOI] 10.1016/j.scitotenv.2021.148887 PMC 바로가기 [Article Type] Article
Implementation of serological and molecular tools to inform COVID-19 patient management: protocol for the GENCOV prospective cohort studyCOVID-19 환자 관리를 알리는 혈청학적 및 분자적 도구의 구현: GENCOV 전향적 코호트 연구를 위한 프로토콜Article Published on 2021-09-302022-09-11 Journal: BMJ Open [Category] SARS, 변종, 진단, [키워드] Adult patients antibody Antibody Response antibody titres Antigen approved association B-cell baseline blood sample Blood samples Characteristics clinical Clinical data clinical trials Clinical Trials Ontario collected conducted correlated COVID-19 COVID-19 patient COVID-19 symptoms determine Diagnosis diagnostics disease severity Ethics evaluate genetic difference genetic differences genetic marker Genetic markers genetics Genome Genome sequencing genomic variant Greater Toronto Area hospitals Host host genome identify immune response immunology Infection information isotype leucocyte Lineage molecular molecular diagnostics molecular diagnostics. Observational cohort study outcome outcomes participant Patient patients with COVID-19 peer-reviewed physiological response prospective cohort study protocol receiving receptor Regression regression models Research Research Ethics review SARS-COV-2 infection SARS-CoV-2 virus sequence information sequenced Sequencing serological severity severity of COVID-19 Symptom System T-cell the antibody response the SARS-CoV-2 virus Variability Viral viral genomes viral neutralisation virus genome [DOI] 10.1136/bmjopen-2021-052842 PMC 바로가기 [Article Type] Article
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resourcesArticle Published on 2021-02-092022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] ACE2 affected Agricultural genetics Animal breeding ANPEP Asian component Coronavirus infection Data mining described Describing Diseases DPP4 European example Genetic Genetic markers Genomics Host host gene host receptor Infection Infectious diseases investigated involved mechanisms Mild Next-generation sequencing one health Perspective Population Population genetics populations protein sequence proteinase reservoir resource resources risk TMPRSS2 Variability variant viral infections viral spike protein [DOI] 10.1038/s41598-021-82956-0 PMC 바로가기 [Article Type] Article
Pharmacogenomics of COVID-19 therapiesReview Article Published on 2020-08-182022-10-04 Journal: NPJ Genomic Medicine [Category] 바이오마커, 유전자 메커니즘, 임상, 치료제, [키워드] ABCC2 adverse effects Alter association Baricitinib Chloroquine clinical Concentration coronavirus disease Corticosteroids COVID-19 COVID-19 patient CYP2C8 CYP2D6 drug Effect Efficacy Efficacy and safety Evidence Favipiravir FDA food genetic marker Genetic markers genetic variants global pandemic Hemolysis high mortality Hydroxychloroquine hydroxychloroquine/chloroquine information inhibitors interferon Interferon beta-1b labeling liver morbidity notable other variants pharmacogenetics pharmacogenomics QT prolongation Remdesivir ribavirin risk ruxolitinib searched SLC28A2 SLC29A1 SLCO1A2 SLCO1B1 Therapies therapy Tocilizumab Toxicity variant viral infection website [DOI] 10.1038/s41525-020-00143-y PMC 바로가기 [Article Type] Review Article
Matching STR and SNP genotyping to discriminate between wild boar, domestic pigs and their recent hybrids for forensic purposesArticle Published on 2020-02-212023-08-29 Journal: Scientific Reports [Category] E형 간염, [키워드] Genetic markers PCR-based techniques [DOI] 10.1038/s41598-020-59644-6 PMC 바로가기 [Article Type] Article
Identification and characterization of SEC24D as a susceptibility gene for hepatitis B virus infectionArticle Published on 2019-09-172023-06-03 Journal: Scientific Reports [Category] B형 간염, [키워드] Genetic markers hepatitis B [DOI] 10.1038/s41598-019-49777-8 PMC 바로가기 [Article Type] Article
Forensic genetics and genomics: Much more than just a human affair법의학 유전학 및 유전체학: 단순한 인간 문제 그 이상Review Published on 2017-09-212022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Analysis attacks bioinformatics bioterrorism criminal DNA Evidence faster Forensic Genetic markers genetic material genetics greater increasingly less microorganisms plants Sequencing species variety while [DOI] 10.1371/journal.pgen.1006960 PMC 바로가기 [Article Type] Review
Gene-Environment Dependence Creates Spurious Gene-Environment Interaction유전자-환경 의존성은 가짜 유전자-환경 상호작용을 생성한다Report Published on 2014-09-042022-08-07 Journal: American Journal of Human Genetics [Category] 유전자 메커니즘, [키워드] Accuracy addition biological processe biological processes can not causal variant condition dependence disease epidemiological example gene-environment dependence gene-environment interaction genetic marker Genetic markers IMPROVE in addition to independent Interaction leads Linkage disequilibrium marker mediation no interaction Pleiotropy power risk Sample size shown SNP Spurious statistical interaction susceptible [DOI] 10.1016/j.ajhg.2014.07.014 PMC 바로가기 [Article Type] Report